A functional polymer, sulfonated polysulfone (SPS) with a degree of substitution of 0.10, was prepd. and then blended with cellulose diacetate (CA) as the matrix polymer for the prepn. of molecularly imprinted polymer (MIP) membranes via phase inversion from a casting soln. contg. a template. Polyethylene glycol was shown to be compatible with these polymers and was subsequently used as pore forming agent. Optimization studies, with the aim to enhance the membrane permeability, were carried out with respect to solvent, polymer blend compn., and total polymer concn. The effects of pore structure were also studied by membrane water uptake and sp. surface area measurements. In conclusion from these investigations, DMSO was chosen as the solvent, the CA/SPS compn. was maintained at 90/10 (wt./wt.) to minimize non-specific template binding and the total polymer concn. was set at 13 wt.%. MIP membranes based on CA/SPS blends with Rhodamine B (RhB) as template were prepd. using the optimized conditions. Results for re-binding of RhB during filtration through MIP as well as Blank membranes, prepd. without RhB, provide evidence for surface imprinting of the porous membranes.