Biology-inspired synthesis of compound libraries
In: Cellular and Molecular Life Sciences - CMLS, Vol. 65 (2008), No. 7/8, pp. 1186 - 1201
Title:
Biology-inspired synthesis of compound libraries
Author:
Kaiser, MarkusUDE
- LSF ID
- 52590
- ORCID
-
0000-0002-6540-8520
- Other
- connected with university
Year of publication:
2008
Appears in
Title in English (abbreviated):
Cell. mol. life sci.
Place of publication:
Berlin
Publisher:
Springer
in:
Vol. 65 (2008), No. 7/8, pp. 1186 - 1201
ISSN
ISSN
ZDB ID
Note:
ab 53.1997
Type of resource:
Text
Abstract:
Biologically active small molecules represent the basis for chemical biology applications in which small molecules are used as chemical tools to probe biological processes. In this report, we review two approaches to design and synthesize compound libraries for biological screenings, i.e., diversity-oriented synthesis (DOS) and biology-oriented synthesis (BIOS).