Wilk, Wolfram; Waldmann, Herbert; Kaiser, Markus:
γ-Pyrone natural products – a privileged compound class provided by nature.
In: Bioorganic & medicinal chemistry : a Tetrahedron publication for the rapid dissemination of full original research papers and critical reviews on biomolecular chemistry, medicinal chemistry and related disciplines, Jg. 17 (2009), Heft 6, S. 2304 - 2309
2009Artikel/Aufsatz in ZeitschriftBiologie
Fakultät für Biologie
Titel:
γ-Pyrone natural products – a privileged compound class provided by nature.
Autor(in):
Wilk, Wolfram; Waldmann, Herbert; Kaiser, MarkusLSF
Erscheinungsjahr
2009

Abstract:

In “Biology Oriented Synthesis” (BIOS), the inherent biological relevance of natural products is employed for the design and synthesis of compound libraries. Towards this end, library generation in BIOS is focused on compound classes from biologically relevant space such as the natural product space or also the drug space and only scaffolds of these areas of proven relevance are employed for synthesis of small focused libraries with limited diversity. We here present a short overview of γ-pyrone natural products, highlighting their biological properties and their potential applicability in a BIOS of a compound library.