Abstract:

Studies problems related to modelling, control and monitoring of circulatory systems with an artificial heart. First, presents a pulsatile model of cardiovascular systems. This model has a well-grounded physiological basis and includes several reflex control systems, such as baroreceptor feedback loops, and nonlinearities of vessel compliance, which are inherent in the body. In addition, develops a model of an artificial heart. Based on these models, proposes a pulse frequency modulated (PFM) control scheme for the circulatory systems with an artificial heart. This scheme enables us to regulate the blood pressure and volume of the circulatory systems properly. To monitor the behaviour of the circulatory systems with an artificial heart an observation scheme is finally presented, with which the blood pressure and stroke volumes of the circulatory system can be estimated by using only the measurements of the driving pressure of the artificial heart.